![]() ![]() Preoperatively, in vivo screening for aberrant adrenal receptors revealed an aberrant response of cortisol secretion on metoclopramide challenge. ![]() ![]() Adrenal imaging revealed bilaterally enlarged adrenal glands with 131-I adosterol uptake hence, BMAH was diagnosed. Cushing’s signs and serum cortisol at 16.2 µg/dL with undetectable adrenocorticotropic hormone indicated adrenal Cushing’s syndrome. ![]() Here, we describe a 61-year-old postmenopausal Japanese woman with unsatisfactorily controlled hypertension who was referred to us for further investigation due to her pre-obesity characteristics (body mass index 28.4 kg/m 2). However, little is known about whether this aberrant response is retained after unilateral adrenalectomy. Sho Tanaka, 1 Midori Fujishiro, 2 Yoshihiro Nakamura, 1 Yoshinari Hatanaka, 1 Masanori Abe 1ġDivision of Nephrology, Hypertension and Endocrinology, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan 2Division of Diabetes and Metabolic Diseases, Nihon University School of Medicine, Tokyo, JapanĪbstract: Aberrant cortisol secretion responses after exogenous stimuli such as upright posture, eating a mixed meal or receiving agents influencing aberrant G-protein-coupled receptors in adrenal glands, are often observed in patients with bilateral macronodular adrenal hyperplasia (BMAH). ![]()
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